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 Monday, April 28, 2008
Delving into DNA
Posted by Allison
No matter how much experience you have in genealogy, you're always a beginner with some type of research or resource. Right now, I'm a newbie at genetic genealogy: I took my first DNA test last week. If you're contemplating diving into your own gene pool, watch this video of my experience to learn what you're in for: Genetic Genealogy
4/28/2008 10:15:59 AM (Eastern Daylight Time, UTC-04:00)
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 Monday, March 24, 2008
Donated DNA to SMGF? You Could Get a $19.50 Profile
Posted by Diane
If you've participated in the Sorenson Molecular Genealogy Foundation’s (SMGF) DNA study, you may be able to get your genetic genealogy test results for just $19.50. SMGF’s collaboration with the DNA-enabled social networking site Genetree has provided an avenue for SMGF to release the DNA profiles in what study director Scott Woodward calls a “compelling, confidential” way. To be eligible for the offer, you must have ordered an SMGF participation kit prior to Oct. 23, 2007, and returned the properly completed kit to SMGF postmarked no later than Dec. 31, 2007. If that’s you, you’ll be able to access your mitochondrial (mt) DNA profile (with genetic information passed from mothers to their children), along with the pedigree information you submitted to SMGF, online through Genetree. You’ll need a free Genetree basic membership to view your profile. It’ll take about two weeks for your request to be filled— get instructions for obtaining your results on Genetree's "unlock" page. The SMGF study started in 2000 at Brigham Young University’s Center for Molecular Genealogy, with researchers collecting blood samples and pedigree charts at genealogy conferences. The goal? Build a database of DNA and corresponding genealogical information. Several years ago, the project outgrew the university and moved to SMGF, where the database now contains nearly 100,000 DNA samples and more than 6 million corresponding genealogical records from people in 170 countries. You can search SMGF databases and contact potential relatives through the site, but until now, participants didn’t receive their test results. On Genetree, which launched in beta last October, you can create profiles for yourself and deceased relatives, add DNA test results or order an mtDNA test ($99 or $149), search for relatives, share memories, build a family tree, and invite relatives and friends to participate. Genealogy Web Sites | Genetic Genealogy
3/24/2008 10:55:15 AM (Eastern Daylight Time, UTC-04:00)
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 Wednesday, March 12, 2008
... and DNA Consulting becomes DNA Testing Systems
Posted by Diane
In another family history industry renaming, genetic genealogy testing company DNA Consulting is now called DNA Testing Systems, says founder Donald N. Yates. Yates also announced he's relocated the company from Santa Fe, NM, to Scottsdale, Ariz. DNA Testing Systems will add DNAPrint Genomics’ line of biogeographical ancestry tests to its product selection. Those offerings include the AncestrybyDNA test (sold under the name Whole DNA), which breaks your genetic heritage into Native American, East Asian, Sub-Saharan African and Indo-European anthropological groups. Genetic Genealogy
3/12/2008 9:46:18 AM (Eastern Daylight Time, UTC-04:00)
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 Thursday, January 24, 2008
SeqWright Launches Genome Profiling Service
Posted by Diane
Someone else wants to map your genome. Houston-based SeqWright Inc. just launched SeqWright GPS, a genomic profiling service that evaluates your miniscule genomic variations called Single Nucleotide Polymorphisms, or SNPs (“snips”). Similar to the recently launched 23andMe, SeqWright customers can use online tools to learn your risk for certain diseases, compare your traits to those of family members who’ve been tested and explore your ancient ancestry. You won’t learn whether you’re related to someone, but rather, which broadly defined population groups you most likely come from. SeqWright’s Web site is less friendly-looking than 23andMe's, which obviously benefits from Google’s financial investment, and doesn’t make quite as much effort to explain scientific lingo. At $998, SeqWright’s test is $1 less than 23andMe’s. Genetic Genealogy
1/24/2008 4:04:29 PM (Eastern Standard Time, UTC-05:00)
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 Thursday, January 10, 2008
Morse Adds One-Step Tools for Genetic Genealogy
Posted by Diane
Steve Morse, creator of the One-Step search tools Web site, has added genetic genealogy utilities to his site. Rather than find matches in genetic genealogy databases (we’d love to see that utility), these free tools help you learn more about your DNA test results. Three of the tools work using data from the FamilyTreeDNA Web site, so customers of other companies will have to pass on those. The tools include: - FamilyTreeDNA Markers: Use this one to view your Y-chromosome test results from FamilyTreeDNA—just enter your kit and code numbers.
- Haplogroups: Anyone who's taken a Y-DNA test can get a pretty good idea of his haplogroup by entering his STR marker values. (If you're a FamilyTreeDNA client, just enter your kit and code number.) As Morse explains, haplogroups are defined by SNP markers, but you usually don’t get SNP values in a Y-DNA test report. STR marker values, though, can predict a haplogroup.
- Group Chart: Here, you can generate a DNA chart for a group of people for easier test results comparison. Each group member must have tested with FamilyTreeDNA.
- Distances: FamilyTreeDNA clients can use their group chart (generated with the Group Chart tool) to compute the genetic distances among members of the group.
- Migration Details: Select your haplogroup from a dropdown menu to get a description of your ancient ancestors’ migrations across the globe. You’ll see shifts in haplogroups and the mutation numbers that defined the shifts, along with the geographic location and time range the mutation took place.
- Migration Map: Select your haplogroup to generate a visual representation of the migration details described above.
See the DNA toolkit on FamilyTreeMagazine.com for genetic genealogy advice, explanations and resources. Steve Morse also has created One-Step Tools for searching online databases such as EllisIsland.org and Ancestry.com (you must subscribe to Ancestry.com to see search results from its databases). You'll find hints for using the tools in the February 2007 Family Tree Magazine. Genealogy Web Sites | Genetic Genealogy
1/10/2008 1:18:52 PM (Eastern Standard Time, UTC-05:00)
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 Wednesday, December 12, 2007
New Research Helps on FamilyTreeMagazine.com
Posted by Diane
I wanted to let you know about a few goodies we’ve recently added to our Web site. First is a group of free research guides—let’s call them “kits.” Each kit is a collection of tips, background information, Web sites, books and CDs to help you with these research topics: At the top of each page in the kit, you’ll see an In This Article list of what’s on that page. At the bottom of each page, use the More on This Topic section to link to other pages in the kit. For your researching convenience, we’ve also put together a free PDF guide to locations and contact information for FamilySearch’s Family History Centers in the United States and Canada. You can download that from www.familytreemagazine.com/fhcs. Genealogy Web Sites | Genetic Genealogy | Oral History | Research Tips
12/12/2007 10:12:22 AM (Eastern Standard Time, UTC-05:00)
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 Monday, December 10, 2007
DNA Tests Verify Pets' Pedigrees, Too
Posted by Diane
Now four-legged family members can get in on the genetic genealogy act, too. That’s right—owners of mixed-breed pooches can learn about their pets’ pedigrees so they can confidently answer the question, “So what kind of dog is that?” Fern Glazer, our writer who got genetic genealogy experts to answer readers’ common DNA quandaries for the March 2008 Family Tree Magazine (on newsstands mid-January), uncovered a couple of companies that do doggy DNA testing: - Last August, DNA Print Genomics launched Doggie DNAPrint 1.0, a test costing about $100 that examines 204 canine markers obtained from a cheek swab to reveal your dog’s ancestry population (its relationship to four ancient ancestral breeds). The company is also building a purebred database that eventually will let you compare your dog's DNA for accurate breed identification.
- Mars Veterinary recently rolled out The Wisdom Panel MX test. Using a blood sample your veterinarian takes, the test detects specific combinations of genetic markers that can reveal the breed heritage of your dog.
Genealogy fun | Genetic Genealogy
12/10/2007 5:21:44 PM (Eastern Standard Time, UTC-05:00)
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 Tuesday, November 27, 2007
NY Times Asks "How Helpful is Ethnic DNA Testing?"
Posted by Diane
Did everyone read the article on ethnic genetic genealogy testing in Sunday’s New York Times? It was somewhat critical of the industry with regard to DNA tests for African origins. Reporter Ron Nixon said test results are often conflicting and confusing, and testing companies focus more on marketing than on communicating the limitations of ethnic DNA testing. Nixon sent his own DNA to five companies for a mitochondrial (mt) DNA test and got strikingly different results: Reports named from two to 12 ethnic groups, for a total of 25 possibilities. Nixon also interviewed representatives of several test companies, as well as Harvard historian and "African-American Lives" host Henry Louis Gates. Gates’ first mtDNA test in 2000 reported Egyptian roots; one from another company in 2005 concluded he had European, not Egyptian, ancestry. One reason for mixed results is testing companies’ proprietary comparison databases of DNA profiles from modern people. Databases may be skewed toward particular ethnic groups and not represent other groups. Furthermore, people have been moving around Africa for eons. Your DNA could match someone who lives in a particular area today, but whose ancestors came from elsewhere. Another issue is that there’s still so much to learn. In our November 2007 Family Tree Magazine African-American research guide, Roots Project director Bruce Jackson, PhD, said “We have a poor understanding of the genetics of African groups ... Identical genetic markers or signatures (called haplotypes) are found among different African ethnic groups for reasons that are not clear.” Jackson went on to note scientists have studied only 1 percent of African ethnic groups, which doesn’t even include all those who were sources of the slave trade to North America. Gates is attempting to address these issues by partnering with FamilyTreeDNA on AfricanDNA, a project offering DNA tests paired with genealogy research services for $888 to $1,077. If that's not in your budget, do this: Research "on paper" as much as you can before turning to DNA. More African-American resources are out there than many people realize. (See our online toolkit and updates on this blog for tips.) Then decide what you want DNA testing to tell you and carefully research your options to pick the best test. Make sure you understand the limitations of DNA testing: As you see here, results can be inconclusive, and you don’t learn where specific ancestors came from. If you don’t understand your results, ask your testing company for help and consult sources such as Trace Your Roots with DNA by Megan Smolenyak Smolenyak and Ann Turner (Rodale, $16.95). Share your thoughts on the Times' article in the FamilyTreeMagazine.com Hot Topics Forum. African-American roots | Genetic Genealogy
11/27/2007 12:16:37 PM (Eastern Standard Time, UTC-05:00)
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 Monday, November 26, 2007
First Retail DNA Paternity Test on Shelves
Posted by Diane
Sorenson Genomics has come out with the first retail DNA paternity kit, and it yields results in three to five days. The Identigene DNA Paternity Test Kit is on sale at Rite-Aid stores in California, Oregon and Washington for $29.99 plus a $119 lab processing fee. That beats the $245 price tag for a paternity test through Identigene’s Web site. Customers send in cheek swabs from the alleged father and child with the lab fee, and can get their results online, by fax or mail. It sounds a lot easier than being on one of Maury Povich’s “Who’s your daddy?” shows. For genealogical purposes, this test could be handy in cases of adoption or “nonpaternity events.” You need DNA samples from both parties, and it can only tell you whether a parent-child relationship exists—not whether the two are related in another way (tests for other relationships are available through Identigene and other labs). We’re interested in future implications, though: Can a retail genetic genealogy test be far behind? Genetic Genealogy
11/26/2007 12:20:39 PM (Eastern Standard Time, UTC-05:00)
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 Tuesday, November 20, 2007
23andMe Profiles Your Genome
Posted by Diane
A new DNA testing Web site with financial backing from Google purports to “help you understand your DNA.” It’s called 23andMe, a name that refers to the 23 pairs of chromosomes making up your genome. The site’s test examines all your DNA (rather than focusing on the X or Y chromosome) for SNPs (pronounced snips), which are variations that can show relationships between people. You have about 500,000 SNPs linked to everything from health issues to whether you like Brussels sprouts. To use 23andMe, you order a kit, send in a cheek swab and later log on to get your DNA profile. It provides information on your phenotypes, or observable traits resulting from interactions between your genes and the environment. Your phenotypes can tell you about your ancestry and about how your genes may affect your health. The site's Gene Journal helps you understand your results with tools including an Odds Calculator (plug in variables such as age, ethnicity and genetic information to see what medical conditions you should be concerned about), a glossary and research article archive. You can use ancestry tools such as a Global Similarity Map that compares your genome to people around the world, which can shed light on where your ancestors came from. You also can consult a Maternal Ancestry Tree to learn about your family’s ancient roots. The test is pricey at $999 per kit. What you can learn is more about health than genealogy, and it’s bound to be controversial as non-doctors try to absorb medical information. So of course, after you use all the cool tools, you’ll want share your findings with your doctor. Genealogy Web Sites | Genetic Genealogy
11/20/2007 1:33:57 PM (Eastern Standard Time, UTC-05:00)
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 Friday, November 16, 2007
AfricanDNA Testing and Research Service Launches
Posted by Diane
Henry Louis Gates Jr., the Harvard professor who hosted PBS’ “African-American Lives” series, is partnering with genetic genealogy company FamilyTreeDNA to launch AfricanDNA. The new service will provide provide African Americans with family tree research in addition to DNA testing. The genealogy part is important, says Gates, because of the limits of genetic testing. “The available DNA data are not by any means complete, and these tests will not yield the names of any of the individuals on our distant family trees—just the general geographic areas in which our ancestors lived. Sometimes the tests yield multiple exact tribal matches, making it necessary for historians to interpret the most plausible result.” AfricanDNA offers mitochondrial DNA and Y-DNA tests for $189 each ($378 for both). Results are compared to FamilyTreeDNA’s database of DNA profiles from around the world. A board of scholars from institutions such as Emory University and Boston University will help interpret customers’ results. Test takers can opt for the Genealogy Package ($888 for one test or $1,077 for both), which includes a documented lineage as far back as records permit. African-American roots | Genetic Genealogy
11/16/2007 4:13:00 PM (Eastern Standard Time, UTC-05:00)
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 Friday, October 26, 2007
Social Networking Meets Genetic Genealogy
Posted by Diane
The Sorenson Molecular Genealogy Foundation (SMGF) is combining two of the latest genealogical developments—DNA testing and online social networking—in its partnership with the GeneTree beta Web site. Users can sign up for a free GeneTree account and create home pages with photos, family trees, multimedia and DNA results. All named ancestors automatically get pages, too, which families can add to. A niftily named tool called DNAvigator searches the SMGF mitochondrial (mt) DNA test results database for matches to yours, then compares the associated lineages and locations, and presents the results “in an intuitive visual representation” like the one here. Matching people can get in touch through GeneTree.  You also can order mtDNA tests, which both men and women can take, through GeneTree. Y-DNA tests will soon be available for men. Some who contributed DNA samples to the SMGF databases—those who requested test kits before Oct. 22 of this year, and send in their samples before Nov. 22—are eligible to receive their test results for a processing fee. That includes participants back in the early days of the project, when it was hosted by Brigham Young University, says SMGF spokesperson Peggy Hayes. Learn more by calling (800) 344-7643 or e-mailing SMGF. SMGF, the nonprofit arm of Sorenson Companies, has been collecting researchers’ DNA samples and associated family tree information for years to build its free Y-DNA and mitochondrial DNA databases. GeneTree used to offer paternity testing, but now Sorenson's IdentiGene division has taken over that business. Genealogy Web Sites | Genetic Genealogy
10/26/2007 2:11:32 PM (Eastern Daylight Time, UTC-04:00)
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 Tuesday, October 16, 2007
DNA Ancestry Emerges From Beta
Posted by Diane
Ancestry.com’s DNA Ancestry site has emerged from beta offering Y-DNA and mitochondrial tests (ranging from $149 to $199) and promising Ancestry Member Tree users will soon be able to add their test results to the information in their trees. Public trees are searchable, so theoretically, you could find the name of a candidate for your great-grandfather, take a DNA test and see if you’re a match to his descendant. DNA Ancestry seems user-friendly, with streamlined test ordering, and genetic genealogy information (including sample test result reports) linked on the right side of the home page. You also can listen to Megan Smolenyak Smolenyak, Ancestry.com’s chief family historian and co-author (with Ann Turner) of Trace Your Roots With DNA (Rodale, $14.95), talk about genetic genealogy on NPR. People who get tested with DNA Ancestry are automatically notified of matches in its DNA database. You’ll be able to enter results from other labs in the database, which isn’t yet available but will be free. Of course, you’ll want to take the site’s marketing with a grain of salt. An ad on Ancestry.com says “Looking for your ancestors? Just say ‘aah.’” Kind of gives the impression you take a test and boom, you know your missing ancestor’s name and place of birth. Yes, you might take a test and immediately learn you unquestionably match a cousin who knows your family history back to the Dark Ages. But we’re not to the point where that’s possible for all. You’ll probably need to plug your test results into several databases before finding a match, and those matches may be iffy enough that you have to do more genealogical research before you can say for sure whether and how you’re related. You can get more details on DNA Ancestry on its FAQ page and blog. Look in an upcoming Family Tree Magazine for our article featuring answers to genealogists' pressing genetic genealogy questions. Genealogy Web Sites | Genetic Genealogy
10/16/2007 11:15:36 AM (Eastern Daylight Time, UTC-04:00)
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 Tuesday, October 02, 2007
SMGF DNA Database About to Balloon
Posted by Diane
If you've taken a DNA test to learn more about your ancestry, have you searched the Sorenson Molecular Genealogy Foundation DNA database lately? The nonprofit Sorenson Molecular Genealogy Foundation (SMGF) just announced it’s on course to collect more than 30,000 DNA samples by the end of this year, for a total of more than 100,000 samples and corresponding genealogical records. Mitochondrial DNA (passed from mothers to their children) makes up the bulk of the additions. The growth is partly due to SMGF’s efforts to collect DNA internationally, including in Panama, Mongolia, Thailand and Africa. The new DNA and genealogies will pad SMGF's test results database, which contains information about more than six million ancestors from 172 countries. You can search it for free. You also can contribute your DNA and pedigree by requesting a test kit. Note you won’t get test results—for that, you’ll need to use a commercial service. (Sorenson Genomics no longer offers commercial tests through Relative Genetics. Back in June, The Generations Network acquired Relative Genetics and its Y-Match results database.) See SMGF’s FAQ for more details on contributing DNA, and watch upcoming Family Tree Magazines for our answers to your genetic genealogy questions. Genealogy Web Sites | Genetic Genealogy
10/2/2007 2:57:52 PM (Eastern Daylight Time, UTC-04:00)
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 Thursday, September 13, 2007
DNA Consulting to Launch Genetic Genealogy Forum
Posted by Diane
DNA Consulting is planning an online forum called DNA Ancestor Communities for genealogists who’ve taken DNA tests. I got a sneak peek at the site, to launch this week at dnacommunities.com. The forum has boards for people whose tests have revealed European, Native American, Melungeon and “World” (non-European) heritages, plus a general Q&A board. On request from DNA Consultants customers, monitors for each category will search updated versions of the OmniPop DNA comparison database. (Users tested by another company can order searches and analysis for $120.) The OmniPop database, which DNAConsulting licenses, contains DNA test results from volunteers. It’s also free online but can be pretty tricky for laypeople to use. DNA Ancestor Communities monitors also can help forum members learn to use another online comparison database from the European Network of Forensic Science Institutes. DNA Consulting staff will answer genetic genealogy questions on the site's General Discussion board. Principal investigator Donald Yates says he hopes the site will help people understand results from DNA Consulting's DNA Fingerprint test, but you don’t have to be a customer to join the forum. Genetic Genealogy
9/13/2007 8:06:43 AM (Eastern Daylight Time, UTC-04:00)
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 Tuesday, September 04, 2007
Ancestry.com Launches DNA Beta Site
Posted by Diane
Back in June, The Generations Network (TGN) acquired Relative Genetics and its test results database from Sorenson Genomics. ( See our blog report.) Now we’re seeing the fruits of that union on the DNA Ancestry beta site. There, you can order Y-DNA tests for $149 (33 markers) or $199 (46 markers), or mtDNA tests for $179. On the overview and ordering pages, you get information on the tests, and you can see a sample test results report. Trace Your Roots with DNA (Rodale, $14.95) co-author Megan Smolenyak Smolenyak became TGN’s chief family historian early this year, so expect good-quality background information. Those with a free Ancestry.com registration will be able to search a test-result database and enter results from other companies’ tests. The Relative Genetics site will be phased out by the end of 2007. See DNA Ancestry's FAQ page for more information. Look for more genetic genealogy help in upcoming issues of Family Tree Magazine. Also see the October 2006 Family Tree Magazine’s user-friendly testing guide (sold out from our back issues store, but ask for it at your library). Family Tree Magazine articles | Genealogy Web Sites | Genetic Genealogy
9/4/2007 9:24:34 AM (Eastern Daylight Time, UTC-04:00)
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 Monday, June 18, 2007
Ancestry.com Re-enters the DNA Business
Posted by Diane
It was only a matter of time. Ancestry.com plans to sell DNA test kits and add a genetic genealogy database to its array of research offerings. It’s made possible by a partnership between Ancestry.com’s parent company, The Generations Network (TGN), and Salt Lake City-based Sorenson Genomics—one of the country’s largest DNA testing labs, the creator of the Sorenson Molecular Genealogy Foundation (SMGF) genetic genealogy database, and until now, the owner of consumer genetic genealogy testing lab Relative Genetics. Relative Genetics will close, and its customers and Y-Match test results database will become part of TGN. Ancestry.com will market the tests, with results to be added to Ancestry.com’s database, and host the surname projects formerly at Relative Genetics. Relative Genetics spokesperson Peggy Hayes says the free Sorenson Molecular Genealogy Foundation database, which isn't part of Relative Genetics, is not part of the partnership. "SMGF will continue its mission as a philanthropic organization," she added. Ancestry.com's DNA tests will cost less than $200 and be available later this summer. Sorenson's labs will provide the testing kits and analyze customers' DNA. The DNA test results database will be free at Ancestry.com. Former Relative Genetics customers will automatically become Ancestry.com registered users, who can access the site’s free services. The customers will be able to control privacy settings, or opt out altogether by contacting Relative Genetics before July 15. (see Relative Genetics' FAQ page for more on what this development means for customers). You may remember the GenetiKit, TGN predecessor MyFamily.com’s first foray into genetic genealogy. Also a partnership with Relative Genetics, the GenetiKit Y-DNA test kit debuted in 2002 for $219 and faded away a few years ago. Genealogy Industry | Genetic Genealogy
6/18/2007 10:39:45 AM (Eastern Daylight Time, UTC-04:00)
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 Tuesday, June 12, 2007
Tracing the Lost Colony Through DNA
Posted by Diane
Genetic genealogy could help researchers figure out what happened to the Lost Colony on Roanoke Island, NC. It’s one of America’s most enduring mysteries: What happened to the 100-plus settlers who landed on the island in 1587? When the governor, John White, was finally able to return there in 1590, he found it deserted and, inexplicably, the word Croatoan carved into a tree. Theories abound: Spanish explorers destroyed the settlement, the colonists tried unsuccessfully to return to England, they assimilated into American Indian groups. The last speculation is what Brighton, Mich., genetics lab DNA Explain, along with the North Carolina-based Lost Colony Center for Science and Research, will study. Researchers will test the Y-DNA and mitochondrial DNA lines of people identified through genealogical research as possible descendants of Roanoke colonists. For comparison, they also may test the colonists’ known relatives in Britain. Well, my curiosity is certainly piqued! Have you solved a family mystery through DNA testing? Let us know by posting a comment. Genetic Genealogy
6/12/2007 12:14:36 PM (Eastern Daylight Time, UTC-04:00)
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